Looking for 2-star Prestonsburg hotels? You have come to the right hotel reservations website. We have many two star Prestonsburg hotels, motels & Inns, like Best Western Of Wise, Best Western Plus Louisa and Comfort Suites Prestonsburg West. Read customer reviews and find cheap and discounted hotel rates on these 2 star Prestonsburg hotels. Many room types are also available at these hotels, motels and inns like standard room with king bed or 2 queen beds and hotel suites. With room level amenities like Free parking, Iron and ironing board and Satellite TV. These 2 star properties have good balance on price and comfort at reasonable cost or room rates and conveniently located near U.S. 23 Country Music Highway Museum, University of Pikeville, and Mountain HomePlace.